FSTAB is basically a utility that runs mount commands @ boot. You basically take the command line to mount a disk and insert it into FSTAB. But It has a BUNCH of configurable parameters.
Fstab is also used for mounting things like BINDing Directories.
I prefer to mount via label, but you can mount via UUID. UUID's can change if you say move the files to a new disk. So I stick with Labels and use GParted to Label each drive.
nofail,nobootwait!! Very Important, if they are not there and the system tries to boot it will fail trying to mount the drives!